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Causes of Depression and a Closer Look at What Depression Is

 What Is Depression?

Virginia J. Duffy PhD, Psychiatric Nurse Practitioner

People use the word depression loosely to mean a number of different moods. I prefer to use the term “clinical depression” to distinguish the type of depression that may improve with medication. Clinical depression is more than the "blues” or sadness. It is not something a person can "just get over" or talk themselves out of. Clinical depression is at least partially based on brain biochemical imbalance (we are still in early stages of understanding this) and often runs in families. Stress and psychological factors also play an important role, although we do not fully understand the causes and factors that result in clinical depression

Common symptoms of depression include sad or irritable mood, loss of interest / energy, poor or excessive sleep and appetite, difficulty with concentration and memory, and physical complaints. Medication is often necessary in serious depression and MAY be helpful with less severe types.

Types Of Depression

There are four types of depression listed in the current Diagnostic and Statistical Manual (DSM 4 TR). The intent of this manual is to help those in the mental health field make accurate diagnoses. One of its goals is to make the diagnosis more consistent between providers. Unfortunately it is often used haphazardly.

1. Adjustment Disorder With Depressed Mood

A reaction to a stressor. (Loss of a loved one, job, physical illness, move etc.) This type of disturbed mood is usually mild and self-limiting. When symptoms last longer than 6 months another type of depression should be considered. Counseling, therapy and support may be sufficient treatment. Medication is not usually necessary.

2. Dysthymia

A chronic low-level depression. It can be very debilitating and may be a part of the personality. It also can be difficult to treat with medication; therapy is recommended.

3. Major depression

A severe form of depression with multiple symptoms as described above. Medication is necessary and usually very effective. Therapy may be helpful after acute symptoms have abated. Suicide potential must be monitored. This can be severe enough to cause psychotic (loss of reality) symptoms, such as delusions and hallucinations.

4. Bi-Polar 1 Disorder

A cycle of depression and elevation of mood (hypomania or mania). This can be very severe, with psychotic symptoms. Antidepressants may be avoided due to risk of switching the mood to mania. This condition needs expert psychiatric treatment usually with mood stabilizing medication. (By the way there is a significant amount of confusion and disagreement about this diagnosis especially between Bipolar 1 and Bipolar 2 disorders. Bipolar 2 disorder is less severe and medication is often not necessary.)

Differential Diagnosis (problems that may be confused with depression)

• Hypothyroidism (low thyroid)
• Grief
• Substance abuse
• Chronic pain
• Anxiety
• Side effects of medication

Target Symptoms Of Depression

Identifying and describing specific target symptoms is crucial if treatment is to be monitored and its’ effectiveness evaluated. It is easy to forget how severe symptoms were when depression is resolved. The more specific the target symptoms are, the better to keep track of changes. Some examples of target symptoms are listed below.

• Sleep Disturbance (difficulty falling or staying asleep, awakening often during the night, early morning awakening, oversleeping)
• Concentration / Memory Problems
• Low Energy Level
• Irritability
• Physical complaints
• Change in Appetite (decreased or increased)
• Lack Of Motivation / Interest
• Mood Changes (sadness, anger hopelessness)

Is Depression a Chemical Imbalance?

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